Diabetes News for June 17, 2001
20 to 22% off on books and scales

Pollution Hazardous To Your Heart
Growing Stem Cell Issue
Certain Fats May Inflate Type 2 Risk
Does Diabetes Shorten Life?
Pricey Drugs May Cost Seniors Health
Exercise Your Way To Happiness?
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Pollution Hazardous To Your Heart

Air pollution is often associated with heath problems such as allergies, asthma, and dry eyes. However, new research shows that it might also be connected to an increased risk of heart attack.

A recent study of 772 people in the Boston area who'd had heart attacks showed that people were more likely to have a heart attack after increases of air pollution. The research was conducted by doctors at Harvard University in Boston, Massachusetts, who have published their study in the journal Circulation (volume 103; June 12, 2001).

At the conclusion of the study, researchers found that those who were exposed to high levels of air pollutants, such as automobile emissions, experienced an increased risk of heart attack of 50% to 70%. A significant increase in air pollution in the 2 to 24 hours prior to the participants' symptoms was also associated with an increase in the risk of heart attack.

Scientists believe that deposits of particles in the lungs trigger an inflammatory response that may slow blood flow and increase the risk of blood clots. For people whose arteries are already blocked by plaque, this response may lead to a heart attack. People who have other risk factors for heart attack like diabetes or high blood pressure should take note of pollution levels that may increase their risk.

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Growing Stem Cell Issue

The issue of whether or not stem cells should be allowed in research continues to grow in intensity. The issue is politically controversial, as is demonstrated by the division of beliefs within the Bush administration.

Stem cells are cells that have the potential to develop into any type of cell in the body, and thus have the potential to cure a variety of diseases. Research using stem cells has been stopped by President Bush until a decision by Health and Human Services Secretary Tommy Thompson and other members of a review committee can be reached. This decision is supposed to be made this summer.

Bush has expressed support of federal funding for research with stem cells that have been obtained from adults. However, some scientists doubt that adult stem cells have the same potential as embryonic stem cells, and have called on Bush to resume federal funding of embryonic stem cell research.

Legislation introduced by Rep. Chris Smith (R-N.J.) has added to the controversial issue. Smith has created the ''Responsible Stem Cell Research Act of 2001,'' which specifies that the government will support stem cell research using adult cells, but not embryonic cells. This is in contrast to the legislation introduced by Rep. Jim McDermott (D-Wash.) on June 5, which would allow the federal funding of research on embryonic cells. Those who support Smith's legislation include 45 members of the House and conservative groups such as the National Right to Life (NRL) and the Coalition of Americans for Research Ethics (CARE).

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Certain Fats May Inflate Type 2 Risk

Certain health issues affect people differently along gender lines. A new study suggests that the intake and processing of trans fatty acids may increase the risk of Type 2 diabetes for women.

The advantage of trans fats is that at room temperature they will harden into a solid form, unlike the polyunsturated vegetable oils from which they are formed. One example is "corn oil" margarine in which the corn oil has been highly modified into dangerous trans fats. Another is Crisco. Trans fats have been recognized for several years as being as dangerous or more dangerous than saturated fat in the development of heart disease. Recently, however, trans fat was studied by doctors at Harvard University in Boston, Massachusetts to determine their effect  on women's risk of developing Type 2 diabetes.

The researchers studied medical and dietary information from over 84,000 women between the ages of 34 and 59 who did not have diabetes, heart disease, or cancer at the beginning of the study in 1980. The researchers updated the dietary information of the participants three times over the following fourteen years.

Results of the study, which is published in the American Journal of Clinical Nutrition (volume 73, pages 1001-1002 & 1019, June 2001), indicated that the women's intake of total fat, saturated fat, and monounsaturated fat did not influence the risk of diabetes. However, only a 2% increase in calories from trans fats increased the risk of developing Type 2 diabetes by 39%. Increasing cholesterol intake by 24 milligrams per day was also found to increase the risk of diabetes by 12%. In contrast, a 5% increase in calories from polyunsaturated fat lowered the risk of diabetes by 37%.

The researchers do not claim that trans fatty acids and cholesterol cause diabetes. However, they believe that the study results indicate that these fat types increase the risk of Type 2 for women who are already at risk. Those who have a particularly high risk are people with insulin resistance, and a major cause of insulin resistance is the presence of free fatty acids in the blood. 

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Does Diabetes Shorten Life?

Diabetes is associated with numerous health issues, including heart disease, nerve damage, and eye damage. A new study indicates that diabetes may decrease overall life expectancy as well.

The study was conducted by researchers at Middlesbrough General Hospital in northern England, who published their findings in the British Medical Journal (June 2001). They conducted a six-year study of over 4,800 people with diabetes, and compared the number and causes of death in people with diabetes who lived in one of the poorest areas of England with the rest of the population in the same area.

The researchers found that there was an obvious decrease in life expectancy in those with Type 1 diabetes, as 25% of them died during the study, which is a mortality rate about 2.2 times the national average. People with Type 2 diabetes also had a shortened life expectancy. Those who had been diagnosed with the disease before the age of 40 had a mortality expectancy that was eight years shorter than those without diabetes.

Because all the study participants came from poor areas, the findings may be limited to people with diabetes in low economic areas. Researchers hope that their findings will increase awareness of the life-threatening health risks that may be associated with diabetes.

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Pricey Drugs May Cost Seniors Health

Although inflation accounts for increases in costs for most products, the cost of prescription drugs is increasing at a rate that far surpasses inflation.

A study of the increasing costs of medication has been conducted by the consumer advocacy group Families USA. The group used claims data from the year 2000, and the PRIME Institute at the University of Minnesota then developed a list of the most common prescription drugs used by seniors. These drugs were ranked by the number of prescriptions used.

The group found that the cost of the top 50 drugs used by seniors rose 6.1% over one year, compared to the inflation rate of 2.7%. Of the drugs that sold the most, 38 rose at least 1.5 times the rate of inflation, and over one-third rose at least three times the rate of inflation. One of the drugs with the greatest increase in cost was the diabetes drug Glucophage, manufactured by Bristol-Myers Squibb. The cost of the drug increased by 15.5%, which is almost six times the rate of inflation. 

Glucophage will come out of patent later this year and its cost is expected to fall as generics arrive. However, two minor modifications of Glucophage called Glucophage XL (extended release) and Glucovance (Glucophage combined with a sulfonylurea, glyburide) will continue to be patented for several more years. Costs for these patented versions are expected to remain quite high.

For seniors on a fixed income, the increased cost of medication is particularly upsetting, as certain medications might be too expensive to be part of a realistic health plan.

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Exercise Your Way To Happiness?

Although the benefits of exercise on physical health are clear, it is not always acknowledged that exercise can also lead to better overall mood and mental health. Researchers at Johns Hopkins University in Baltimore, Maryland hope that their recent study will prove that definitively.

The participants in the study included 36 men and women between the ages of 55 and 75. All of the participants were in good physical health. Those who had the greatest endurance during fitness tests, and who had low levels of body fat, also had fewer reports of tension, anxiety, anger, and depression.

The findings, which were presented at the annual meeting of the American College of Sports Medicine in Baltimore (June 2001), do not indicate exactly why exercise may improve mental health. Researchers speculate that the correlation may be between fitness and higher participation in life. These individuals might also be more involved in recreational activities, have better self-image, and be more independent. Any of these factors could contribute to happiness, and are good reasons to exercise.

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