Diabetes News
Week of April 16, 2000

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EU Collaborates On Artificial Pancreas
Shock Therapy For Gastroparesis
On-Line Diabetes Consultation
Antioxidize In Moderation
Health Nuts, Seeds, Grains And Veggies
Ginseng May Lower Blood Sugars
Weight-Loss Drug May Work For Type 2
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EU Collaborates On Artificial Pancreas

An European research consortium hopes to improve blood sugar control by taking human error out of the process, by developing an insulin pump linked to an internal glucose sensor.

Researchers from several European countries, collectively called the Disetronic Group, are currently working on a project known as ADICOL (Advanced Insulin Infusion with a Control Loop). Their goal is to create software to help an internally-implanted sensor measure and display blood sugar concentration. If the measurement does not match critical levels, the sensor would emit an alarm, and trigger the insulin pump to dispense the precise dose required.

The ADICOL project appears be well-supported, both monetarily and intellectually. The EU is contributing a significant amount of money for the project's budget. Researchers will be from Disetronic, the pump therapy specialists and the universities of Graz and Perugia, the German centers Fraunhofer Institute for Biomedical Engineering and SensLab GmbH, the City University of London, and the Danish firm Judex.

This project, with a current budget of EUR 5.3 million, represents the first time the EU has contributed this much money for medical technology.

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Shock Therapy For Gastroparesis

One of the more debilitating complications in diabetes is gastroparesis, where damage to the nerves of the digestive tract hampers the movement of food through the digestive tract. Irregular digestion leads to poor blood sugar control since it becomes difficult to match insulin doses to the entry of glucose into  the blood stream. Severe nausea and vomiting may also be present, causing poor nutrition and starvation. One possible treatment for this is a new, FDA-approved device called Enterra.

Medtronic, Inc. was recently granted a humanitarian device exemption (HDE) from the FDA for its Enterra Therapy, which uses electrical stimulation of the stomach to combat gastroparesis.

So far, about 90 people have received Enterra Therapy, largely through participation in clinical studies underway since 1995. The promising results of these studies helped Medtronic receive the HDE, which is granted only for devices that help people with rare medical conditions unresponsive to standard  treatment. 

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On-Line Diabetes Consultation

Can an internet service manage diabetes for people who don't have the time to visit their doctor on a regular basis? 

A new company known as e-MEDx has an interesting answer to this question with the launch of three web-based programs for various health care problems. One, called e-SelfCare for Diabetes, provides a link between people with diabetes, their primary care physicians, and diabetes care specialists.

The program works by having the person with diabetes fill out a comprehensive risk-assessment questionnaire each month, plus an ongoing health diary once a day or week, depending on the individual. From this information, a graph is produced to give feedback to the individual. The information can be electronically forwarded to the person's doctor, or printed out before an office visit. 

An online clinician is reviews each person's information regularly. If the data suggests poor health or high risk factors, the clinician contacts the person, and, if necessary, the person's doctor.

The site also has e-PHA and e-Consult services, and all three services can be accessed on their website. The company hopes to save time and money for providers and patients by making preventative care easy and accessible.

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Antioxidize In Moderation

Some people claim that taking large amount of antioxidants (such as vitamins C and E) may prevent diseases like diabetes, cancer, Alzheimer's disease, and heart disease. According to the Institute of Medicine, a U.S. government advisory panel, that claim is a little too optimistic.

The panel has said that most people in America already consume recommended levels of antioxidants through their normal diet, and that supplements are often unnecessary. Also, an intake of antioxidants that is too high may result in health problems. For example, an excessive intake of vitamin C can cause diarrhea, too much vitamin E might increase the risk of stroke due to it's blood-thinning properties, and too much selenium can result in hair loss and brittle nails.

While raising cautions, researchers also recommended raising the RDA or recommended daily allowance for antioxidants. New recommendations are that women consume 75 milligrams of vitamin C per day, and men consume 90 milligrams. Smokers need about 35 milligrams more, since they are likely to have cell damage. This is actually a higher RDA than before, though only by about 15 milligrams.

The panel recommends that all people consume 15 milligrams of vitamin E per day which can be obtained from nuts, seeds, and leafy green vegetables. In addition, the intake of selenium should be limited to 55 micrograms for both men and women.

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Health Nuts, Seeds, Grains And Veggies

In contrast with the government's recommendation, the Institute of Medicine of the National Academies has recently issued a report stating that antioxidant-rich foods with vitamins C and E are beneficial in preventing disease. The report says that consuming antioxidant phenolics and phytochemicals in foods like grains, leafy green vegetables, nuts, and legumes may help delay the onset of diseases like diabetes, heart disease, cancer, and colon dysfunction.

In a recent publication of the Journal of the American College of Nutrition (Vol. 19, No. 1, pgs. 61-67), Dr. Gene Spiller outlines his research on the benefits of the consumption of tocopherols. These antioxidants are found in tree nuts. His study shows that the tocopherols stop free radicals in the body, thereby preventing oxidative damage to cells. He also concludes that diets that are rich in tocopherols benefit lipoproteins, and improve colon function.

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Ginseng May Lower Blood Sugars

Drinking a cup of tea may provide more benefits than you think, particularly if that tea is made from ginseng.

In a recent study conducted by the University of Toronto and St. Michael's Hospital in Toronto, researchers found that taking ginseng root before a meal may actually lower blood sugar levels for people with Type 2 diabetes.

In the study, published in the April 9th issue of the Archives of Internal Medicine, researchers compared the blood sugar levels of people with and without Type 2 diabetes, after they'd consumed three grams of American ginseng. Results showed that those with Type 2 who'd taken the ginseng either 40 minutes prior to a meal, or during the meal, had a twenty percent drop in blood sugar levels. Those without diabetes also had a drop in blood sugar, but only when the ginseng was ingested before the meal.

Ginseng has been touted for its many benefits for centuries. This benefit is definitely one that calls for more research.

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Weight-Loss Product May Work For Type 2

Lose weight and diabetes at the same time? Sure, but how can you do it?

PacificHealth Laboratories, Inc. has recently developed a product known as Satietrol which is designed to activate the body's natural appetite suppressant, cholecystokinin (CCK). After you eat, the body releases the protein CCK, which makes you feel full. Satietrol works by activating this protein, so that the person who takes it feels full faster. By taking the drug 10-15 minutes before eating, Satietrol is designed to help people eat less at mealtime.

In studies, people taking Satietrol, by consuming fewer calories, lost an average of nine pounds in six weeks. PacificHealth is now beginning research to see if Satietrol can be used as a food additive, and possibly as a treatment for Type 2 diabetes.

To learn more, please visit the company's website or call 1-877-SATIETY (728-4389).

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Information provided by The Diabetes Mall @ http://www.diabetesnet.com 
Books, gram scales, and more: (800) 988-4772 or (619) 497-0900
Copyright © 2000 by Diabetes Services, Inc
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